Scientists manage to destroy ex vivo "reservoirs" of HIV
The current methods of treating #HIV infection imply the need for patients to receive lifelong therapy, since even the most modern drugs are not yet able to eliminate the viral "reservoirs" that are hiding in immune cells. A group of researchers from the Pasteur Institute was able to determine the characteristics of #CD4-infected T-lymphocytes — their metabolic activity allowed HIV to multiply — and using inhibitors of metabolic activity to destroy these infected cells- “#reservoirs” ex vivo. The results of the study were published in the journal Cell Metabolism on December 20th.
18 十二月 2018 13:07
HIV vaccine protects non-human primates from infection
The new study shows that rhesus macaque monkeys can be prompted to produce neutralizing antibodies against one strain of HIV that resembles the resilient viral form that most commonly infects people, called a Tier 2 virus. The research also provides the first-ever estimate of vaccine-induced neutralizing antibody levels needed to protect against #HIV.
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14 十二月 2018 13:11
Michel Sidibe will leave UNAIDS in June 2019
The head of the United Nations Program on #HIV / #AIDS (#UNAIDS), Michel Sidibé, announced that he would resign early in June of the coming year. The resignation of the UNAIDS head has become known against the backdrop of a scandal that has flared up in the organization in connection with the statements of employees about sexual harassment.
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23 十月 2017 05:57
Cost-Effectiveness of PrEP — Business Case
Cost-effectiveness of #PrEP were discussed in the 25th lesson of the #PrEParing online course. The lecture was presented by the associate professor of the Department of #Epidemiology at Johns #Hopkins University, therapist David Dowdy. The main focus was on the cost-effectiveness of preventive interventions in key populations. An interactive efficiency calculator introduced in the #PLOS One by a group of scientists was explained in this lesson too.
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28 九月 2017 04:49
HIV Pre-Exposure Prophylaxis (PrEP) Online Course at Coursera Review. Day 24 of 42.
The model of the maximum nurse-led #PrEP coverage helps to reduce costs. Familiar to us director of nursing at Magnet over at #Strut from the #AIDS#Foundation of San Francisco, Pierre-Cedric Crouch, explained how in the #Magnet clinic of the project Strut from San Francisco solves this problem.
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27 九月 2017 04:49
Should your clinic offer PrEP? Course review Day 23 of 42.
Should your #clinic offer #PrEP, pre-exposure #HIV prophylaxis? Demetre Daskalakis, the Assistant Commissioner for the Bureau of HIV #AIDS #Prevention and Control in the New York City Department of #Health and Mental #Hygiene, spoke about the current approaches in the US to the issue of expanding access to PrEP. The lesson will be of interest to social workers from the field of sexual health and HIV prevention and health organisers. Dr Dakalaskis will set an example of successful social worker initiatives when people were able to develop and implement PrEP programs in some #US cities.
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11 八月 2017 12:39
HIV Pre-Exposure Prophylaxis (PrEP) Online Course at Coursera Review. Day 22 of 42.
We start the 22th lesson of the #PrEParing #MOOC on the topic “Paying for #PrEP: Patient Assistance Programs”. The lecture was read by Jess LaRicci, PrEP coordinator at Johns Hopkins School of Nursing Reach Initiative.
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1.2. History of discovery
Immunodeficiency virus exists broadly in nature — many species of animals are infected by it. The immunodeficiency virus (IDV) which was found in monkeys is very similar to the human immunodeficiency virus. HIV appears to have spread to humans from monkeys infected with the immunodeficiency virus in the early twenties of the last century.
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1.3. Description, structure and lifecycle of the virus
Human immunodeficiency virus (HIV) infects cells of the immune system containing CD4 receptors on their surface: T lymphocytes (t-helpers), monocytes, macrophages and some others. After penetrating into cells, the virus begins to reproduce, which further provokes the destruction and death of infected cells. The virus escapes from the dead cells and infects new CD4 cells. CD4 cell count gradually gets so low that the body loses its ability to combat infections and viral diseases that do not pose a risk for people with a normal immune system.
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2.1. Diagnostics and prevention
The HIV infection is distinguished by a long absence of symptoms. Diagnosis of the HIV infection is established through laboratory tests: by detecting antibodies to HIV. The first few weeks after the virus enters the body is the eclipse phase when HIV antibodies cannot be detected.
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2.2. Transmission routes
The virus transmission paths are well researched. Gone are the days when it was thought that HIV infection is a disease that affects only drug users, commercial sex workers and men who have sex with men (MSM). Anyone can get infected with HIV, regardless of social status, wealth, sex, age, and sexual orientation.
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地图
亲爱的朋友，
为了向HIV和其他STI感染风险者提供帮助，我们从最具权威的HIV组织，药房，实验室处收集最新数据。
这些信息可以通过交互式地图获得，您可以在这里找到最近的提供HIV治疗的诊所/综合诊所，可以进行HIV检测的实验室，或一个HIV感染者社区。
U=U运动 (#UequalsU)
我的生活+在东欧和中亚地区组织的信息和教育活动 "U=U" （“无法检测到等于不可传播”，#UnqualsU，#НравноН）旨在传达一个信息，即HIV阳性者在病毒载量无法被检测到时，不能将病毒通过性行为传染给另一个人。
许多研究表明，在血清不一致的夫妇中，HIV阳性伴侣接受ARV治疗并保持无法检测到的病毒载量，则没有HIV性传播病例的发生。
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