Scientists manage to destroy ex vivo "reservoirs" of HIV
The current methods of treating #HIV infection imply the need for patients to receive lifelong therapy, since even the most modern drugs are not yet able to eliminate the viral "reservoirs" that are hiding in immune cells. A group of researchers from the Pasteur Institute was able to determine the characteristics of #CD4-infected T-lymphocytes — their metabolic activity allowed HIV to multiply — and using inhibitors of metabolic activity to destroy these infected cells- “#reservoirs” ex vivo. The results of the study were published in the journal Cell Metabolism on December 20th.
18 December 2018 13:07
HIV vaccine protects non-human primates from infection
The new study shows that rhesus macaque monkeys can be prompted to produce neutralizing antibodies against one strain of HIV that resembles the resilient viral form that most commonly infects people, called a Tier 2 virus. The research also provides the first-ever estimate of vaccine-induced neutralizing antibody levels needed to protect against #HIV.
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14 December 2018 13:11
Michel Sidibe will leave UNAIDS in June 2019
The head of the United Nations Program on #HIV / #AIDS (#UNAIDS), Michel Sidibé, announced that he would resign early in June of the coming year. The resignation of the UNAIDS head has become known against the backdrop of a scandal that has flared up in the organization in connection with the statements of employees about sexual harassment.
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23 October 2017 05:57
Cost-Effectiveness of PrEP — Business Case
Cost-effectiveness of #PrEP were discussed in the 25th lesson of the #PrEParing online course. The lecture was presented by the associate professor of the Department of #Epidemiology at Johns #Hopkins University, therapist David Dowdy. The main focus was on the cost-effectiveness of preventive interventions in key populations. An interactive efficiency calculator introduced in the #PLOS One by a group of scientists was explained in this lesson too.
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28 September 2017 04:49
HIV Pre-Exposure Prophylaxis (PrEP) Online Course at Coursera Review. Day 24 of 42.
The model of the maximum nurse-led #PrEP coverage helps to reduce costs. Familiar to us director of nursing at Magnet over at #Strut from the #AIDS#Foundation of San Francisco, Pierre-Cedric Crouch, explained how in the #Magnet clinic of the project Strut from San Francisco solves this problem.
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27 September 2017 04:49
Should your clinic offer PrEP? Course review Day 23 of 42.
Should your #clinic offer #PrEP, pre-exposure #HIV prophylaxis? Demetre Daskalakis, the Assistant Commissioner for the Bureau of HIV #AIDS #Prevention and Control in the New York City Department of #Health and Mental #Hygiene, spoke about the current approaches in the US to the issue of expanding access to PrEP. The lesson will be of interest to social workers from the field of sexual health and HIV prevention and health organisers. Dr Dakalaskis will set an example of successful social worker initiatives when people were able to develop and implement PrEP programs in some #US cities.
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11 August 2017 12:39
HIV Pre-Exposure Prophylaxis (PrEP) Online Course at Coursera Review. Day 22 of 42.
We start the 22th lesson of the #PrEParing #MOOC on the topic “Paying for #PrEP: Patient Assistance Programs”. The lecture was read by Jess LaRicci, PrEP coordinator at Johns Hopkins School of Nursing Reach Initiative.
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1.2. History of discovery
Immunodeficiency virus exists broadly in nature — many species of animals are infected by it. The immunodeficiency virus (IDV) which was found in monkeys is very similar to the human immunodeficiency virus. HIV appears to have spread to humans from monkeys infected with the immunodeficiency virus in the early twenties of the last century.
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1.3. Description, structure and lifecycle of the virus
Human immunodeficiency virus (HIV) infects cells of the immune system containing CD4 receptors on their surface: T lymphocytes (t-helpers), monocytes, macrophages and some others. After penetrating into cells, the virus begins to reproduce, which further provokes the destruction and death of infected cells. The virus escapes from the dead cells and infects new CD4 cells. CD4 cell count gradually gets so low that the body loses its ability to combat infections and viral diseases that do not pose a risk for people with a normal immune system.
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2.1. Diagnostics and prevention
The HIV infection is distinguished by a long absence of symptoms. Diagnosis of the HIV infection is established through laboratory tests: by detecting antibodies to HIV. The first few weeks after the virus enters the body is the eclipse phase when HIV antibodies cannot be detected.
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2.2. Transmission routes
The virus transmission paths are well researched. Gone are the days when it was thought that HIV infection is a disease that affects only drug users, commercial sex workers and men who have sex with men (MSM). Anyone can get infected with HIV, regardless of social status, wealth, sex, age, and sexual orientation.
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Video Blog Life4me+
Dear friends! We launched the YouTube blog for information about the Life4me+ app, about our work and about HIV in general.
Video Blog Life4me+
Dear friends! We launched the YouTube blog for information about the Life4me+ app, about our work and about HIV in general.
Map
Dear friends,
We collect updated data on the most important HIV organizations, pharmacies, laboratories, both for people living with HIV, and for those who are at risk for HIV and other sexually transmitted infections.
This information is available via interactive maps where you can find the nearest clinic/polyclinic which provides HIV treatment, a laboratory where you can take an HIV test, or a community of people living with HIV.
Help contacts
Sometimes we need to talk directly to someone or to ask for advice. Here you will find hotline phone numbers for your city or region.
Now we provide information on Russia and Ukraine and continue to collect data on other countries.
If you want to inform us about the error or give us new information about the hotline in your city and / or region — send us an e-mail.
About Life4me+
One of the main goals of Life4me+ — is to prevent new cases of HIV and other STIs, hepatitis C and tuberculosis. So we talk about HIV and other diseases: how to protect yourself from them, how to live with them.
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Campaign U=U (#UequalsU)
The information and education campaign "U=U" ("Undetectable equals untransmittable", #UequalsU, #НравноН), organized by Life4me + in the Eastern Europe and Central Asia region, aimed at disseminating information that an HIV-positive person with an undetectable viral load can not transmit the virus to another person sexually.
Many studies have shown that in a sero-discordant couple where the HIV-positive partner took ARV therapy and maintained an undetectable viral load, there were no reported cases of sexual transmission of HIV.
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